CD14 anticorps (PE)

N° du produit ABIN317123

L’anticorps Souris Monoclonal anti-CD14 a été validé pour FACS. Il convient pour détecter CD14 dans des échantillons de Souris.

Aperçu rapide pour CD14 anticorps (PE) (ABIN317123)

Antigène: CD14

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD14 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: BiG53

Détail du produit anti-CD14 anticorps (PE)

Attributs du produit: Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

Purification: Purified IgG prepared by affinity chromatography on Protein G

Immunogène: Recombinant mouse CD14

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: Use 10 μL of neat antibody to label 1x10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1 mL distilled water

Buffer: PBS pH 7.4 containing 0.09 % Sodium Azide and 1 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD14

Antigène: CD14

Autre désignation: CD14

Sujet: CD14 is a 55kD a glycophosphoinositol-linked cell surface protein that also exists in a soluble form. Expression of CD14 is restricted to the myeloid lineage and is predominantly expressed on peripheral blood monocytes, weakly expressed on granulocytes and absent on myeloid progenitors. The CD14 Molecule acts as a pattern recognition receptor, which binds lipopolysaccharide (LPS) and other microbial products such as lipoteichoic acid, lipoproteins and peptidoglycan. Binding of LPS to CD14 mediates the innate immune response to LPS and requires the Toll-like receptor-4 (TLR4)/MD-2 complex for effective signalling.Synonyms: Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein

UniProt: P10810

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades